Programm Advances in Therapeutic Approaches

Session 1 - Targeted Protein Degradation

Radosław Nowak - Targeting C2H2 transcription factors for degradation with molecular glues

Nicolas Thomä - Oncogenic transcription factors, and how to get rid of them

Bhavesh Parmar - Time-resolved high-throughput proteomics to understand the dynamics of protein degradation

Sarah Köllner - The Sorting Games: Sortilin-targeting degraders

Varun Shah - Discovery of Novel Molecular Glue Degraders

Martin Schwalm - Functional live-cell systems to test inhibitors targeting the ubiquitin-proteasome system

Session 2 - Technology Advances: from imaging to computational approaches

Kathryn A. Whitehead - Advancement of RNA interference therapeutics

Michael Mitchell - Novel drug delivery technologies of nucleic acids

James Cranley - What can cell atlases teach us about human cardiovascular disease?

Stefanie Kaiser - Advancing RNA analysis in the context of therapy

Session 3 - RNA-based therapeutics

Mustafa Diken - mRNA vaccines against cancer

Dan Peer - Precision nanomedicine

Mathias Munschauer - An RNA-centric perspective on viral infections 

Harald Schwalbe -  Contribution of proteins structures to rational drug discovery

Anne Wacker - Targeting viral RNAs with small molecules

Session 4 - Targeting common mechanisms of human diseases

Uxía Gestal-Mato - Tumor immune evasion through IRGQ-directed autophagy

Andrea Ablasser - Innate immune sensing of DNA as a danger signal

Krishnaraj Rajalingam - Targeting the two co-conspirators RAS and C-MYC in cancer

Maria Vehreschild - Modulating the human gut microbiota for therapeutic purposes

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